The expert of our country finds compatriot's lung cancer and exchanges the induction to click

The expert of our country finds compatriot's lung cancer and exchanges the induction to click
The expert of our country finds compatriot's lung cancer and exchanges the induction to click
It is reported ' Reporter's old heart of inferior Xincai loses reporter Cheng ShouQin) A few days ago, the research group which public health dean Professor Shen HongBing of medical university in Nanjing headed, after paying analyzing to compare the genome of over 8000 lung cancer patients and over 9000 healthy persons, succeed in, sift, find 6 the intersection of lung cancer and the intersection of risk and genetic location order, among them 4 the unit it orders to be lung cancer, crowd of Chinese, of report exchange induction, order for the first time. This result of study is issued on the international top academic periodical " natural heredity " at the beginning of July. It is introduced, this research is the first Chinese crowd's related research of the whole genome of lung cancer. The related research of the whole genome is to study one of the easy perceptual most important and most effective methods of heredity of common complicated disease at present. This research is in the country " 863" Under the subsidy in great project subject and national natural science fund key item,etc., from Nanjing medical university and the institute of oncology of Chinese Academy of Medical Sciences, much of unit cooperation of our country such as Central China University of Science and Technology, Fudan University, Chinese Medical Sciences University, Shanghai Communications University and Guangzhou medical college are finished. According to the introduction of Shen HongBing, this project uses many attitudes (SNP) of high density gene The chip, has measured the genetic mutation of patient and person who contrast in the whole genome range normally of lung cancer of big sample quantity, and big sample, the cases of many stages - contrast collected from Nanjing, Beijing, Shanghai, Wuhan, Shenyang and Guangzhou area are verified, have illness coming on prominently relevantly after discovering 6 hereditary variation and Chinese crowd's lung cancer of 4 chromosome areas. Rs2736100 located in chromosome 5p15 area has gene - environmental reciprocation with state and smoking amount of smoking to make a variation, this danger clicked is particularly prominent in women, non-smoking crowd and lung gland cancer patient. This research results have not only filled in the blank of Chinese crowd's data in the related research of the whole genome of lung cancer, and the molecule mechanism happening in further investigating lung cancer, checking to the sieve of the high-risk group of lung cancer, diagnosing and treating etc. in early days that has important value.


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