My expert proposes the new theory that tumour recurs

My expert proposes the new theory that tumour recurs
My expert proposes the new theory that tumour recurs
It is reported ' Reporter Li TianShu) Why can tumour recur? Researchers think that there are tumour stem cells. A few days ago, the scientific research group that the director of centre of prevention and cure of Zhongshan University's tumour, once benefit of academician of Chinese Academy of Sciences were led newly proposed the new " originated from " of stem cell of tumour for the first time Say, DNA thinking some tumour chemotherapy causes will promote ordinary tumour cells to develop into the tumour stem cell to damage. This may treat result of study that tactics exert an important influence, publish at the intersection of U.S.A. and " the biological The Chemicals " recently to tumour. Once benefit was pointed out newly, the tumour stem cell (CSC) Existence considered to be the thing tumour taking place and the origins of recurring. In radiotherapy of tumour and chemotherapy, ordinary tumour cells are sensitive to treating, easy to eliminate, but tumour stem cell just like fragrant-flowered garlic, cut, lose, can longer than one by one, it is difficult to be destroyed, and will continue producing new tumour cells. The academia generally think, the tumour stem cell comes from and organizes into a malignant transformation of the body stem cell. At the scientific meeting in Fragrant Hills in 2004, once new first proposition of benefit, an important characteristic of tumour cells was that the genome was unstable. The treatment causing DNA to damage, will aggravate the existing genome unstability of tumour cell, strengthen the possibility to produce tumour stem cell. He thinks, the cells emerging can be called the tumour stem cell from organizing the stem cell to cancerate, and the cells produced because of being with unstable genome from ordinary tumour cells should be called " One kind of tumour cells of stem cell " ( SLCC) . In recent years, once benefit was new,etc. to utilize the platform of the national key laboratory of oncology of South China, have further investigated. They find in the nasopharyngeal carcinoma having, growing specially strong ability, can resist chemotherapy and the intersection of stem cell and one kind of tumour cells of radiotherapy really at first ' This research results published magazine) in U.S.A. " cancer research " in 2006 . Thereafter, they clone the monocyte coming from single ordinary tumour cells, shine with the ultraviolet ray, or by causing the chemotherapy medicine that DNA damage to deal with, found finally that could obviously induce the production of one kind of tumour cells of stem cell. A series of research brief on, genome unstability that DNA's damaging causes, can cause ordinary tumour cells to turn into one kind of tumour cells of stem cell. Researchers point out, in the chemotherapy of tumour, DNA damages pharmaceuticals and probably eliminates tumour cells on one hand, on the other hand aggravate the genome unstability, induce ordinary tumour cells to develop into one kind of tumour cells of stem cell. Once benefit was pointed out newly, if this result was confirmed by more laboratories finally, then the therapeutic tactics of tumour should be adjusted correspondingly too. Researchers need what has been assessed chemotherapy of tumour again acts on for a long time, especially treat the use that DNA damaged pharmaceutical with caution.


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