Resist " super bacterium "

Resist " super bacterium "
Resist " super bacterium "
The scientist found one kind and can nearly resist the super bacterium of all antibiotic in some patient who has accepted medical care or travelled in South Asia body recently. The more serious one is, because some of patients are infected with the condition and already died without treatment too seriously. So far, all the suspected infection even the case dies of infecting this kind of bacterium has appeared in countries such as Britain, U.S.A., Canada,etc., the latest news is that a Japenese that go to India to travel has infected the super bacterium too, already the requirement has been in the relevant province of Canada " The super bacterium " It is ready to infect and break out. All these demonstrate, in antibiotic researches and develops the race of evolving with the bacterium, the latter sprint come up, make at the same time world come over to calm down seem, in the intersection of disease and prevailing edge again in the disturbance from first type the intersection of H1N1 and influenza just again. The researcher of trouble Cardiff University, Britain where the new gene got into who protected administration and India Madras university healthily has finished this research together. The scientist has gathered and got 180 bacteria to separate things on the patients of India, Pakistan and Britain, find most Escherichia coli and CrayResearch's uncle's fungus of pneumonia got from it have the superstrong one to able to bear nature, only have it in order to add the ring plainly and glue the fungus plainly and can bring it under control. Further research still finds, the superstrong secret against nature is hidden on a plasmid in bacterium's body. Like mankind, the biochemical characteristic of physiology of the bacterium is still determined by the fact that genetic from essence. But most genes of the bacterium are while arranging in chromosome as bunch, some is dissociated except chromosome. The plasmid is the important carriers of these free genes. The plasmid in the bacterium not only can be duplicated independently, transmit to the subgeneration, can also shift among bacterium. That is to say, did not originally possess a certain property (such as drug resistance) Bacterium accept last medicine from other bacterialy in the plasmids,it is too can become by a members against medicine fungus not to change one's identity suddenly. Carry a kind of NDM-1 (metal - �� - inner amide enzyme 1 in New Delhi) by name on the plasmid that the scientist found this time New for gene,it is that this gene encode enzyme last amide the abilities of rings inner �� in antibiotic, and this ring structure is that most antibiotic kill the key of the bacterium. Trace back to 1928 if it is difficult to divide competition antibiotic and pathogen's inextricably involved trial of strength of the win and defeat, doctor Fleming that London St. Marie hospital worked found of mould that could produce penicillin in his laboratory not very neat for the first time in Britain at that time. Under the continuation efforts of Oxford University scientist's money kindness and Fulton, medical professor of Yale University, later, penicillin is put into rapidly practically and entering and producing stage on a large scale. The antibacterial performance of its high-efficient low toxicity has saved countless lives injured in the battle field of World War II. A lot of incurable diseases - -For instance scarlet fever, diphtheria, pneumonia, syphilis,etc. - -Under the might in penicillin crushes dry weeds and smashes rotten wood, have been inhibited effectively. Because the physiologic and medical award of Nobel that the above-mentioned three people of this achievement have shared 1945 together. However, in obtaining the award and making a speech, Fleming with foresight prophesies one sharply: "In the near future, penicillin will be popularized in the world. Lack the intersection of medicines and patient of knowledge, will reduce dosage is enough to kill all bacteria of he in the body while being very easy, thus enable the production drug resistance of bacteria. " The mass use worldwide of penicillin becomes reality quickly, but unfortunately, Fleming becomes the augury about a same language of prophecy against nature. Main the intersection of function and the intersection of base and the intersection of group and �� - inner the intersection of amide and ring of penicillin can interfere with the intersection of germ and formation of cell wall, make the bacterium dissolve the death, thus play a role in sterilizing and restraining the fungus. However, wish eagerly to let the bacterium be unwilling to await one's doom in existence that is carved in the genome depths. Through evolving, some bacteria are decomposed the ability of inner amide ring. The statistics show, in various bacteria, inner amide enzyme already found has exceeded 200 kinds. These enzymes can all open inner amide ring in common penicillin, very beginning spore fungus plain type, carbon penicillin antibiotic structure. Other bacteria rely on sudden change, has reduced the affinity of one's own and penicillin, have possessed drug resistance too. And the scientist, in order to evade the ability of the bacterium, through transforming to penicillin or aiming at the new antibacterial target to click, develop the second and the third generations of antibiotic, is clearing up the drug resistance of the bacterium constantly, protect and help human health. In this way, the intersection of rival and ahead of decades such as competition such as ground under me you at the the intersection of that couple and match track, get to today. Has extricated oneself from a plight up till now, though while competing and running this, the face-off of antibiotic and pathogen seems that also have advantage of several bodies, but sudden change and evolution of bacterium difficult to carry on in a manner to perceive by mankind always, that is to say this terrific equilibrium may look like straw of the last which overwhelms the camel like that, suddenly broken. Some scientists even think pessimistically, it is very possible under pathogen's threat in the 21st century for the mankind, face not having usable predicament of medicine, even will fall back until the era without antibiotic. In order to avoid the emergence of this kind of circumstances, the experts of a plurality of fields have already taken action. It is to use antibiotic to need what we accomplished at first rationally and try hard to lengthen the life-span of existing antibiotic. For example the medical circle has already formed such antibiotic clinical practice principle, it needn't be advanced to use low-grade antibiotic, the ones that can be solved with a kind of antibiotic do not use two kinds, the light intermediate bacterial infection does not jointly use antibiotic,etc.. In addition, though everybody will produce the side effect harmful to health to take dosage to know antibiotic too much, but it is simply little to take dosage, it is very dangerous to reach the sterilization density too. At the pressure of such inferior choice that the dosage forms of causing death, it is extremely apt to induce bacterium's production against nature. Secondly, the research and development of new antibiotic should accelerate the step. For example mould and plain through the ages put into clinical already more than 50 years, is still taking the laurel of the king of antibiotic. Compare the scene that the new product come out one after another of forty or fifty times of last century, 30 is had recently, though the pathogens one resists the medicine level to improve constantly, but in consideration of cost, risk, devoted to resisting infection the pharmaceuticals that the medicine researches and develops is reducing constantly, and for add the intersection of ring and a few antibiotic such as being plain, criticize and go on the market. As to this, demand urgently to adopt policy and economic means to turn back this state in the governments of various countries. Finally, are opposing the basic research field of the pathogen, need colliding new spark out. The scientist thinks for example having besides killing bacteria directly, through " communication " while blocking bacteria Indirect method while reducing and resisting medicine possibility,it is which get anti-infectious to get up too result. Have scientist besides find, utilize, resist the intersection of medicine and fungus, grow fast characteristic this resisting the intersection of medicine and fungus while being non-, the ones that shoulder between the two " Conflict internally " Also It is hopeful to become a kind of sterilization means. Are though these unimaginably queer ideas here? The flute tool is restrained and smelt of fish> to hide and obey and shine ������ Chen to praise Lu awakely and owe and patch up the amaranth Shou Posthumous to compel, permit pretty thick ���, return �� sigh difficult the intersection of �� and the intersection of Chu and surprised the intersection of what and outspoken Xuan keep fit and strike and is equal to? It is known that the author is a doctor of medicine, scientific squirrel members


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